EXPERIMENTAL EVALUATION OF CELL-MEDIATED IMMUNITY OF HERBO-MINERAL FORMULATION R9 VATI

Abstract

Introduction: The concept of well-being has evolved to encompass not just the absence of illness but also overall health. Rasayana, referring to the nutritional essence that penetrates all body tissues to replenish and nurture them, plays a key role. It enhances longevity, intelligence, youthful vigor, skin health, voice quality, and the robustness of both motor and sensory functions. This is achieved through the use of rasayana herbs, typically administered in powdered or decoction forms, which fortify various dhatu (tissues) and promote overall well-being.

The herbs like ashwagandha, pippali, guduchi, and yashtimadhu, all possessing potent antioxidant properties. Rasasindura, a preparation containing purified mercury (shuddha parada) and sulfur (shuddha gandhaka), is a meticulously processed formulation utilized as a therapeutic agent in treating various ailments. When incorporated into formulations, these Rasaushadhi (herbal medicines processed with metals and minerals) augment the efficacy of herbal remedies, often requiring only small amounts to yield significant effects.

To explore the additional benefits of incorporating Rasasindura into a blend of herbal medicines known for their antioxidant properties, an experimental study was conducted on the test formulation.

Method: Evaluation of cell-mediated immunity, Assessment of humoral immunity through antibody production, Antibody response against SRBC.

Observation and result: R9 V and R9 VWS showed non-significant stimulation of the anti-body formation. The antibody formation represents expression of Humoral immunity hence based on the results obtained it can be inferred that test drug both have mild to moderate Immuno stimulant effect.