QUORUM QUENCHING OF BACTERIA CAUSING DENTAL CARIES THROUGH HERBAL FORMULATION

Abstract

Dental caries is the most prevalent and chronic diseases among dental problems likeperiodontal, tooth loss, gingivitis, toothache, mouth ulcers, gum bleeding andtoothache. It is mainly caused by sugar content in diet and bacteria such asStreptococcus and Staphylococcus. Different methods are used for the prevention ofdental caries such as chemical and natural methods. However, the present study wascarried out to compare the antibacterial activity of aqueous preparation extract ofdried and fresh leaves of Punica granatum, Eucalyptus, Mangifera indica and Acacianilotica at 0.40% and 0.60% against the dental microflora of tobacco chewers plussmoking, tobacco chewers, smokers and normal persons (who are neither tobaccochewers nor smokers). Antibacterial activity of Punica granatum, Eucalyptus, Mangiferaindica and Acacia nilotica have been determined by using agar well diffusion methodagainst the sample. Out of the aqueous preparation of dried leaves extract of Punicagranatum, Eucalyptus, Mangifera indica and Acacia nilotica, Punica granatum was foundmore effective at 0.40% concentration and Acacia nilotica was found least effective at0.40%. But at 0.60% concentration, Eucalyptus was found more effective and Acacianilotica was least effective. While, in case of aqueous extract prepared from freshleaves of the selected plants, Eucalyptus was found more effective at 0.40%concentration, while at 0.60% concentration, Punica granatum was found moreeffective and Acacia nilotica was least effective. On the basis of quick response, Punicagranatum was found more effective in comparison to other tested plant species (i.e.Eucalyptus, Mangifera indica, Acacia nilotica). Punica granatum showed zone of activitywithin 1days after implementation while other extracts showed zone of activity after6-7 days.