Currant Review On Co-Crystals For Topical Drug Delivery

Abstract

Topical drug delivery systems have a rich history, evolving from ancient ointments to sophisticated modern formulations designed to treat various skin disorders and systemic conditions. Recently, co-crystal technology has emerged as a significant advancement in pharmaceutical science, offering the potential to enhance the physicochemical properties of drugs used in topical applications. Co-crystals, which are crystalline structures, composed of two or more molecules, can improve drug solubility, stability, and bioavailability without affecting the drug's pharmacological properties. This review article explores the development and application of topical drug delivery systems, highlighting the advantages and challenges associated with topical administration. It also discusses the role of co-crystals in enhancing the effectiveness of topical treatments by modifying drug properties. The integration of these technologies represents a promising approach to overcoming limitations in current treatments and advancing patient care.