WHAT WE KNOW ABOUT FAST-DISSOLVING TABLETS (FDTs), UPCOMING OPPORTUNITIES IN THE MARKET, HOW WE MAKE THEM, AND WHAT THEY COULD BECOME

Abstract

ABSTRACT— This study set out to find a way to make Mirtazapine & Clebopride tablets that dissolve quickly. The subliming substance was camphor, while the super disintegrants were sodium starch glycolate (SSG) and cross carmellose sodium (CCS). To improve the tablet's porosity, an optimum camphor concentration was applied. To examine the combined impact of two formulation factors, a 32-complete factorial design was utilized: The quantity of SSG and CCS. Older adults and children are more likely to have trouble swallowing tablets, and patients are less likely to take their medication as prescribed when they find the taste unpleasant. Because their muscles and neural systems are still developing, young people sometimes have trouble swallowing. A product of the pharmaceutical industry's never-ending quest for technical perfection is fast-dissolving tablets or FDTs. The patient's cooperation is greatly enhanced with FD pills. Because they provide the benefit of liquid medicine in a solid form, FD tablets are a convenient way to deliver several different medications. Patients of all ages, including those with dysphasia, have shown positive reactions to these new dose formulations. No water or chewing is required for the rapid dissolving or disintegration of FDTs in the mouth. Also known as fast-melts, rapid-melts, porous tablets, fast disintegrating tablets, or orally disintegrating tablets, it is designed for oral administration (FDTs). Children, the elderly, and those who are bedridden, as well as energetic people who are often on the go and do not always have access to water, can all benefit from fast-acting or orally dissolving pills. These pills usually melt or disintegrate in less than 60 seconds when placed in saliva.