Studies of Isopropoxide Bridge Hetero-Bimetallic Complexes: Synthesis, Spectral, Morphology and Antimicrobial Activity

Abstract

Theoretical methods have been utilized to study the solvation of fluoride and chloride ions by water. The number of water molecules has been varied from one to four. Geometry optimization has been performed using B3LYP level employing two different basis sets, 6-311G++ and LanL2DZ and also HF method with 6-311G++ basis set. The results have been compared.Equimolar reaction of [M(sb)Cl]2 with sodium salt of Al(OPri)3 affords the hetero-bimetallic complexes of the general formula [M(sb)(µ-OPri)2Al(OPri)2] 1-6 [where M = Cu, 1-3; Co, 4-6; sb = Schiff base; salicylidene-4 methyl-1-aminobenzene (smabH) 1, 4; salicylidene-1-aminobenzene (sabH) 2, 5 and salicylidene-4-chloro-1 aminobenzene (scabH) 3, 6]. These complexes have been characterized by elemental analysis (C, H, N and Cu), IR, ESI-MS, ESR, PXRD and SEM-EDX studies. These hetero-bimetallic compounds were tested for their in vitro antimicrobial activity against S. aureus (MTCC 902), P. aeruginosa (MTCC 741) and E. coli (MTCC 1687) bacterial strains.